Localization of Chicken Tumor Agent
نویسندگان
چکیده
In osteomyelitis for example, there is frequently the history of an antecedent injury to the affected part, and it may be taken for granted, that this injury in some way predisposes to a localization of bacteria, which may happen to be present in the circulating blood or elsewhere. In syphilis, tertiary lesions appear more frequently in superficial bones which are more exposed to injury than in the deeper ones which are well protected by overlying tissues. Kiedel and Zimmermann (1) have described an interesting case, showing that under certain conditions a syphilitic eruption may follow the lines of tattoo markings in the skin, and further, that certain of the pigments used in tattooing are more active than others in this relation, though whether because of a specific action of the dye substance, or of the degree of reaction that it induces is not known. That al~ inflammatory reactions are not equally effective in promoting the growth of organisms, is well shown by the work of Chesney and Kemp (2), who have demonstrated, that spirochetes will survive better and multiply more rapidly in a recent granulating wound, than in an older subacute lesion.
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Some Factors Determining the Localization of a Chicken Tumor Agent
A localization out of the blood stream of the agent causing a chicken tumor, with the subsequent development of the growth can be brought about in the breast muscle, by inducing in this tissue a reaction by such substances as Scharlach R, tar, embryonic tissue and kieselguhr. Localization in the reaction tissue elicited by kieselguhr takes place relatively infrequently. The earlier stages of th...
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